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S to acuchy aminokwasw poczone wizaniami peptydowymi, ktre tworz si, gdy grupa karboksylowa jednego aminokwasu reaguje z grup aminow innego aminokwasu, uwalniajc czsteczk wody

For most drugs, this is a predictable obstaclepharmaceutical formulators account for it by increasing the oral dose proportionally

Its dramatic age-related decline is significant: plasma concentrations average 200 ng/mL at age 20 but typically plummet to 80 ng/mL by age 60a 60% reduction correlating with visible aging and reduced healing capacity

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